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KMID : 0191120090240030525
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Journal of Korean Medical Science
2009 Volume.24 No. 3 p.525 ~ p.528
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A Case of Primary Adrenal Diffuse Large B-cell Lymphoma Achieving Complete Remission with Rituximab-CHOP Chemotherapy
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Kim Kyung-Min
Suh Chul-Won
Yoon Dok-Hyun
Huh Joo-Ryung
Lim Sung-Nam
Lee Seung-Geun
Sug Lyu-Jin
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Abstract
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Primary adrenal lymphoma is a very rare extranodal lymphoma; its clinical features consist of a high incidence of bilateral adrenal involvement and diffuse large B-cell lymphoma. We report a patient with primary bilateral adrenal diffuse large B-cell lyphoma who achieved complete remission with R-CHOP (rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisone) chemotherapy. A 52-yr-old man presented with fever and progressive fatigue for 3 months. Computed tomography (CT) scans of the abdomen and pelvis demonstrated large bilateral adrenal masses, and a needle biopsy of the left adrenal mass revealed diffuse large B-cell lymphoma. After 6 cycles of R-CHOP chemotherapy, CT scans showed no residual disease. To our knowledge, this is the second report to date of a patient with primary bilateral adrenal diffuse large B-cell lymphoma who achieved complete remission using R-CHOP chemotherapy.
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KEYWORD
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Primary Adrenal Lymphoma, Lymphoma, Large B-Cell, Diffuse, R-CHOP, Complete Remission
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